Cognitive inhibition in trichotillomania and obsessive-compulsive disorder
Cognitive inhibition in trichotillomania and obsessive-compulsive disorder
复制标题
DOI：
10.1016/j.brat.2004.06.014
复制
发表时间：
2005-07-01
影响因子：
4.1
通讯作者：
Wilhelm, S
中科院分区：
文献类型：
--
作者：
Bohne, A;Keuthen, NJ;Wilhelm, S
采用分块线索定向遗忘任务，对21例拔毛症(TTM)、21例强迫症(OCD)和26例健康对照(HC)受试者的认知抑制进行了研究。在对一个单词列表进行编码后，参与者被指示故意忘记这些单词，并记住另一个单词列表。这两份清单都包括与TTM相关的词和中性(与厨房相关)的词，比例相等，与TTM相关的词一般为负价，与厨房相关的词对所有参与者通常为中性价。对记住单词和忘记单词的卓越自由回忆表明认知抑制是完整的。强迫症参与者的表现表明，在抑制负价信息提取方面存在特定缺陷，这在TTM中没有发现。与TTM和强迫症参与者相比，HC参与者对负面信息相当疏忽。总而言之，尽管在这两种障碍中，人们的注意力都不成比例地集中在负面信息上，但认知抑制缺陷似乎是强迫症特有的。(C)2004爱思唯尔有限公司。保留所有权利。
Cognitive inhibition was investigated in 21 trichotillomania (TTM), 21 obsessive-compulsive disorder (OCD) and 26 healthy control (HC) participants using a block cued directed forgetting task. After encoding a word list, participants were instructed to intentionally FORGET these words and to REMEMBER another word list. Both lists included TTM-related and neutral (kitchen-related) words in equal proportions, with the TTM-related words generally of negative valence and the kitchen-related words generally of neutral valence for all participants. A superior free recall of REMEMBER versus FORGET words suggests intact cognitive inhibition. The performance of OCD participants indicated a specific deficit in inhibiting the retrieval of information with negative valence, which was not found in TTM. HC participants, in contrast to TTM and OCD participants, were rather inattentive to negative information. In conclusion, although attention was disproportionately directed towards negative information in both disorders, cognitive inhibition deficits appeared specific to OCD. (c) 2004 Elsevier Ltd. All rights reserved.