Corneal higher-order aberrations induced by overnight orthokeratology
Corneal higher-order aberrations induced by overnight orthokeratology
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DOI：
10.1016/j.ajo.2004.10.006
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发表时间：
2005-03-01
影响因子：
4.2
通讯作者：
Oshika, T
中科院分区：
文献类型：
--
作者：
Hiraoka, T;Matsumoto, Y;Oshika, T
目的：评估夜间角膜塑形术治疗近视引起的角膜高阶像差。设计：前瞻性、非比较性、连续性、介入性病例系列。方法：对 39 名夜间角膜塑形术治疗近视患者的 64 只眼睛进行前瞻性研究，随访至少 3 个月，裸眼视力达到 20/20 或更好。角膜高度数据通过计算机视频角膜摄影术（TMS-2N，Tomey）获得，并使用泽尼克多项式导出波前像差。计算 3 毫米和 6 毫米瞳孔的角膜高阶像差。 结果：角膜塑形术将明显屈光度从 -2.60 +/- 1.13（平均值 +/- SD）屈光度显着降低至 -0.17 +/- -0.31 屈光度（P < .0001，配对 t 检验）。对于 3 毫米（P < .0001，配对 t 检验）和 6 毫米（P < .0001）瞳孔，通过角膜塑形术，三阶（类彗差）像差的均方根 (RMS) 显着增加。通过对 3 毫米 (P < .0001) 和 6 毫米 (P < .0001) 瞳孔进行治疗，四阶 RMS（类球面）像差显着增加。 3 毫米 (P = .0323) 和 6 毫米 (P < .0001) 瞳孔的垂直彗差显着从正变为负。 3 毫米 (P < .0001) 和 6 毫米 (P < .0001) 瞳孔的水平彗差显着增加到正方向。三阶和四阶 RMS 的增加与 3 毫米（皮尔逊相关系数，三阶 RMS 为 r = .452，P = .0001，四阶 RMS 为 r = .381，P = .0017）和 6 毫米（r = .499，P < .0001，r = .455，P = .0017）的近视矫正量呈显着正相关。 .0001) 瞳孔。结论：即使在临床上成功的角膜塑形术病例中，角膜高阶像差也显着增加。高阶像差的增加与近视矫正的幅度相关。 (c) 2005 年，Elsevier Inc. 保留所有权利。
PURPOSE: To evaluate corneal higher-order aberrations induced by overnight orthokeratology for myopia.DESIGN: Prospective, noncomparative, consecutive, interventional case series.METHODS: A prospective study was conducted in 64 eyes of 39 patients with overnight orthokeratology for myopia, who were followed up for at least 3 months and attained uncorrected visual acuity of 20/20 or better. Corneal height data were obtained with computerized videokeratography (TMS-2N, Tomey), and wavefront aberration was derived using Zernike polynomials. Higher-order aberrations of the cornea were calculated for 3- and 6-mm pupils.RESULTS: Orthokeratology significantly reduced manifest refraction from -2.60 +/- 1.13 (mean +/- SD) diopters to -0.17 +/- -0.31 diopters (P < .0001, paired t test). Root-mean-square (RMS) of third-order (coma-like) aberrations significantly increased by orthokeratology for both 3-mm (P < .0001, paired t test) and 6-mm (P < .0001) pupils. Fourth-order RMS (spherical-like) aberrations increased significantly by the treatment for both 3-mm (P < .0001) and 6-mm (P < .0001) pupils. Vertical coma significantly changed from positive to negative for both 3-mm (P = .0323) and 6-mm (P < .0001) pupils. Horizontal coma significantly increased to the positive direction for both 3-mm (P < .0001) and 6-mm (P < .0001) pupils. Increases in the third- and fourth-order RMS showed significant positive correlations with the amount of myopic correction for 3-mm (Pearson correlation coefficient, r = .452, P = .0001 for third-order RMS, r = .381, P = .0017 for fourth-order RMS) and 6-mm (r = .499, P < .0001, r = .455, P = .0001) pupils.CONCLUSIONS: Corneal higher-order aberrations significantly increased, even in clinically successful orthokeratology cases. The increases in the higher-order aberrations correlated with the magnitude of myopic correction. (c) 2005 by Elsevier Inc. All rights reserved.