Late effects of whole-body x-irradiation in the mouse; some gross and histologic aspects of the development of morbidity prior to the terminal state, with special reference to the gonad, uterus, heart, liver, kidney, and submaxillary gland.
Late effects of whole-body x-irradiation in the mouse; some gross and histologic aspects of the development of morbidity prior to the terminal state, with special reference to the gonad, uterus, heart, liver, kidney, and submaxillary gland.
复制标题
小鼠全身 X 射线照射的迟发效应；
作者：
H. Kohn;R. Kallman;C. Berdjis;K. Ome
在几年前开始进行本研究时，已掌握了大量关于实验室动物在全身暴露于外部电离辐射源后发生的急性和晚期变化的资料。到目前为止，这项工作已经得到了广泛的审查（1-9）。3晚期变化大部分是通过在接触后很长时间内检查动物来确定的，通常是在终末期或死亡后立即检查。在暴露后的一个月或两个月内研究急性变化。然而，关于“中间”期间存活动物的变化，即，急性反应消退后和终末状态之前的时期。这是本文的目的，为CAF 1小鼠和BALB/c小鼠，在照射时完全成熟的密切相关的信息提供这样的信息。
When the present studies were initiated several years ago, a considerable body of information was available concerning both the acute and the late changes that occur in laboratory animals after whole-body exposure to external sources of ionizing radiations. By now this work has been extensively reviewed (1-9).3 The late changes were determined for the most part by examining the animals long after exposure, usually in the terminal state or immediately after death. The acute changes were studied during the month or two after exposure. Relatively little specific information was available, however, concerning the changes in surviving animals during the "intermediate" period, i.e., the period that follows the subsidence of the acute reaction and precedes the terminal state. It is the object of this paper to contribute such information for CAF1 mice and closely related information for BALB/c mice, both fully mature at the time of irradiation.