DNA vaccines and immunity to herpes simplex virus.
DNA vaccines and immunity to herpes simplex virus.
复制标题
DNA 疫苗和对单纯疱疹病毒的免疫力。
DOI：
10.1007/978-3-642-80475-5_5
复制
发表时间：
1998
影响因子：
--
通讯作者：
Manickan,E
中科院分区：
文献类型：
--
作者：
Rouse,BT;Nair,S;Rouse,RJ;Yu,Z;Kuklin,N;Karem,K;Manickan,E
Infections by herpes simplex virus (HSV) represent an expensive public health problem. Although only rarely a cause of mortality, HSV infections usually cause painful and often distressing lesions and are particularly troublesome since symptomatic recurrent disease is a common outcome once an individual has been infected. Recurrent lesions on the face and genitalia are the most common expression but in some locations, such as the eye, distressing results such as blindness can occur. As regards HSV infections, in 1985 the Committee on Issues and Priorities for New Vaccine Development of the Institute of Medicine set the following goals: a 50% reduction in symptomatic primary infection, a 75% reduction in the number of recurrences and a 60% reduction in the severity of episodes.
