UNIVERSAL CONTROL MECHANISM REGULATING ONSET OF M-PHASE

UNIVERSAL CONTROL MECHANISM REGULATING ONSET OF M-PHASE
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DOI:
10.1038/344503a0
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发表时间:
1990-04-05
期刊:
影响因子:
64.8
通讯作者:
NURSE, P
NURSE, P
中科院分区:
综合性期刊1区
文献类型:
--
作者:
NURSE, P

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M 期的开始受到所有真核细胞共有的机制的调节。进入 M 期是通过 p34cdc2 蛋白激酶的激活来确定的,该激酶需要 p34cdc2 去磷酸化并与细胞周期蛋白结合。
The onset of M-phase is regulated by a mechanism common to all eukaryotic cells. Entry into M-phase is determined by activation of the p34cdc2protein kinase which requires p34cdc2dephosphorylation and association with cyclin.