Changes in visual acuity in a population over a 15-year period: The Beaver Dam Eye Study
Changes in visual acuity in a population over a 15-year period: The Beaver Dam Eye Study
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DOI：
10.1016/j.ajo.2006.06.015
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发表时间：
2006-10-01
影响因子：
4.2
通讯作者：
Gangnon, Ronald E.
中科院分区：
文献类型：
--
作者：
Klein, Ronald;Klein, Barbara E. K.;Gangnon, Ronald E.
中心点目的：描述15年来视力的变化。中心点设计：以人群为基础的研究。中心点方法：地点：威斯康星州比弗坝。研究对象：在1988年至1990年进行基线检查时年龄在43岁至86岁之间的4068人，此后每五年进行一次随访检查。观察程序：屈光不正后最佳矫正视力，通过修改ETDRS方案进行评估。主要观察指标：视角加倍；视力损害发生率。中心点结果：8%的人视力受损(20/40或更严重)，0.8%的人视力严重受损(20/200或更严重)，7%的人视角加倍，2%的人视力改善。基线年龄在75岁或以上的人更有可能出现视力受损(优势比[OR]12.8，95%可信区间[CI]9.6至17.1，P<；.001)，视角加倍(OR 7.8，95%CI 5.6至10.7，P<；.001)，以及严重视力障碍(OR 20.6，95%CI 9.5至44.8，P<；；0.001)与年龄在75岁以下的人进行比较。中心点结论：这些数据提供了基于人群的估计，在广泛的年龄范围内，15年累计失明发生率。在75岁或以上的人中，视力损害的累积发生率占竞争死亡风险的25%，其中4%是严重的，这表明一个相当大的公共卫生问题，因为这个年龄段的美国人口预计将从2005年的1800万增加到2025年的2800万，增幅为55%。《眼科杂志》2006；142：539-549。(C)2006，Elsevier Inc.保留所有权利。)
center dot PURPOSE: To describe the change in visual acuity in a 15-year period.center dot DESIGN: Population-based study.center dot METHODS: SETTING: Beaver Dam, Wisconsin. PARTICIPANTS: 4068 persons 43 to 86 years of age at the time of a baseline examination in 1988 to 1990, and with follow,up examinations every five years thereafter. SERVATION PROCEDURES: Best-corrected visual acuity after refraction, assessed by a modification of the ETDRS protocol. MAIN OUTCOME MEASURE: Doubling of the visual angle; incidence of visual impairment.center dot RESULTS: Eight percent of the population developed impaired vision (20/40 or worse), 0.8% developed severe visual impairment (20/200 or worse), 7% had doubling of the visual angle, and 2% had improved vision. People 75 years of age or older at baseline were more likely to develop impaired vision (odds ratio [OR] 12.8, 95% confidence interval [CI] 9.6 to 17.1, P < .001), doubling of the visual angle (OR 7.8, 95% CI 5.6 to 10.7, P < .001), and severe visual impairment (OR 20.6, 95% CI 9.5 to 44.8, P < 0.001) compared with people younger than 75 years of age.center dot CONCLUSIONS: These data provide population,based estimates of the cumulative 15-year incidence of loss of vision over a wide spectrum of ages. In people 75 years of age or older the cumulative incidence of visual impairment accounting for the competing risk of death is 25%, of which 4% is severe, indicating a public health problem of considerable proportions as the US population in this age is expected to increase by 55% from 18 million in the year 2005 to 28 million by the year 2025. (Am J Ophthalmol 2006; 142:539-549. (c) 2006 by Elsevier Inc. All rights reserved.)