Adherence to lifestyle modifications after a cardiac rehabilitation program and endothelial progenitor cells A six-month follow-up study

Adherence to lifestyle modifications after a cardiac rehabilitation program and endothelial progenitor cells A six-month follow-up study
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DOI:
10.1160/th13-10-0869
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发表时间:
2014-07-01
影响因子:
6.7
通讯作者:
Fattirolli, Francesco
Fattirolli, Francesco
中科院分区:
医学2区
文献类型:
--
作者:
Cesari, Francesca;Marcucci, Rossella;Fattirolli, Francesco

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据报道,参加心脏康复(CR)计划的急性心肌梗死(AMI)患者的内皮祖细胞(EPCs)增加;但没有关于遵守CR计划期间提供的生活方式建议对EPCs的影响的数据。我们的目的是研究AMI患者接受CR治疗6个月后,坚持生活方式建议对EPCs、炎症和功能参数的影响。在110例AMI患者(90例男性/20例女性;平均年龄57.9 ± 9.4岁)中,在CR结束时(T1)和6个月随访时(T2)测定EPCs、高敏C反应蛋白(hsCRP)、N末端脑钠肽前体(NT-ProBNP)水平和心肺功能检查。在T2时,我们进行了一项问卷调查,评估饮食习惯和体力活动。在T2,我们观察到EPCs减少(p
An increase of endothelial progenitor cells (EPCs) among acute myocardial infarction (AMI) patients participating in a cardiac rehabilitation (CR) program has been reported; but no data On the impact of adherence to lifestyle recommendations provided during a CR program on EPCs are available. It was our aim to investigate the effect of adherence to lifestyle recommendations on EPCs, inflammatory and functional parameters after six months of a CR program in AMI patients. In 110 AMI patients (90 male/20 female; mean age 57.9 +/- 9.4 years) EPCs, high sensitivity C-reactive protein (hsCRP), N-terminal pro-brain natriuretic peptide (NT-ProBNP) levels, and cardiopulmonary testings were determined at the end of the CR (T1) and at a six-month follow-up (T2). At T2 we administered a questionnaire assessing dietary habits and physical activity. At T2, we observed a decrease of EPCs (p