The prevalence of rapid weight gain in infancy differs by the growth reference and age interval used for evaluation.
The prevalence of rapid weight gain in infancy differs by the growth reference and age interval used for evaluation.
复制标题
DOI：
10.3109/03014460.2014.1002533
复制
发表时间：
2016
影响因子：
1.7
通讯作者：
Wisner KL
中科院分区：
文献类型：
--
作者：
Eckhardt CL;Eng H;Dills JL;Wisner KL
婴儿体重快速增加（RWG）可能预示随后的肥胖，但用于评估的生长参考和年龄间隔存在不一致性。本研究评估了RWG的患病率（年龄别体重z评分增加> 0.67）是否因生长参考（2006年CDC参考）和评估的年龄间隔（0-3、0-6、6-12和0-12个月）而不同。使用了来自两项关于妊娠期母亲情绪障碍的观察性研究的单胎足月婴儿的汇总数据（n=161）。使用Cochran's Q和McNemar's检验对RWG患病率与生长参考值和年龄间隔的差异进行了检验。与WHO标准相比，CDC参考产生了0-3月龄间隔内更高的RWG患病率（14%的婴儿额外归类为RWG，p<0.0001）;这种模式在6-12和0-12月龄间隔内逆转。在WHO标准范围内，RWG患病率在不同年龄段之间没有差异，但与CDC参考文献存在差异（范围：0-3个月为22%，6-12个月为4.2%，p<0.0001）。当比较具有不同RWG标准的研究时，建议谨慎。未来的研究应使用2006年WHO标准和一致的评价年龄间隔。
Infant rapid weight gain (RWG) may predict subsequent obesity, but there are inconsistencies in the growth references and age intervals used for assessment. This study evaluated whether the prevalence of RWG (an increase of > 0.67 in weight-for-age z-score) differed by growth reference (2006 CDC references) and age interval of assessment (0–3, 0–6, 6–12 and 0–12 months). Pooled data from singleton term infants from two observational studies on maternal mood disorders during pregnancy were used (n=161). Differences in RWG prevalence by growth reference and age interval were tested using Cochran’s Q and McNemar’s tests. The CDC reference produced a higher RWG prevalence (14% of infants additionally categorized as RWG, p<0.0001) within the 0–3 month age interval compared to the WHO standards; this pattern was reversed for the 6–12 and 0–12 month intervals. RWG prevalence did not differ across age interval within the WHO standards, but did differ with the CDC references (range: 22% for 0–3 months, to 4.2% for 6–12 months, p<0.0001). Caution is advised when comparing studies with different criteria for RWG. Future studies should use the 2006 WHO standards and a consistent age interval of evaluation.