5‐ARI induces autophagy of prostate epithelial cells through suppressing IGF‐1 expression in prostate fibroblasts

5‐ARI induces autophagy of prostate epithelial cells through suppressing IGF‐1 expression in prostate fibroblasts
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DOI:
10.1111/cpr.12590
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发表时间:
2019-03
期刊:
影响因子:
8.5
通讯作者:
Bo-Yu Yang;Chenyi Jiang;Chen-yun Dai;Ruizhe Zhao;Xing-Jie Wang;Yiping Zhu;Yu Qian;F. Yin;Xiang‐Yu Fu;Y. Jing;B. Han;S. Xia;Y. Ruan
Bo-Yu Yang;Chenyi Jiang;Chen-yun Dai;Ruizhe Zhao;Xing-Jie Wang;Yiping Zhu;Yu Qian;F. Yin;Xiang‐Yu Fu;Y. Jing;B. Han;S. Xia;Y. Ruan
中科院分区:
生物学1区
文献类型:
--
作者:
Bo-Yu Yang;Chenyi Jiang;Chen-yun Dai;Ruizhe Zhao;Xing-Jie Wang;Yiping Zhu;Yu Qian;F. Yin;Xiang‐Yu Fu;Y. Jing;B. Han;S. Xia;Y. Ruan

文献摘要

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5α‐reductase inhibitor (5‐ARI) is a commonly used medicine in the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Our study mainly focuses on the mechanism of BPH development after 5ARI treatment.