INDUCTION OF FATTY ALDEHYDE DEHYDROGENASE-ACTIVITY DURING DEVELOPMENT OF BIOLUMINESCENCE IN BENECKEA-HARVEYI
INDUCTION OF FATTY ALDEHYDE DEHYDROGENASE-ACTIVITY DURING DEVELOPMENT OF BIOLUMINESCENCE IN BENECKEA-HARVEYI
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DOI：
10.1016/0006-291x(76)90539-8
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发表时间：
1976-01-01
影响因子：
3.1
通讯作者：
MICHALISZYN, GA
中科院分区：
文献类型：
--
作者：
MEIGHEN, EA;BOGACKI, IG;MICHALISZYN, GA
由于荧光素酶活性的诱导，生物发光在生长后期迅速上升。这种酶在体外催化FMNH2和长链脂肪醛的氧化，从而发光。本文报道了一种醛脱氢酶的发现，该酶对长链脂肪醛的特异性与荧光素酶非常相似。该酶的活性与荧光素酶同时被诱导，为乙醛脱氢酶在哈维伊生物发光系统中的功能暗示提供了有力的证据。
Bioluminescence rises very rapidly in the later stages of growth of B. harveyi due to the induction of luciferase activity. This enzyme catalyzes the in vitro oxidation of FMNH2 and a long chain aliphatic aldehyde resulting in the emission of light. The discovery of an aldehyde dehydrogenase in B. harveyi, which is remarkably similar to luciferase in its specificity for long chain aliphatic aldehydes, is reported. The activity of this enzyme is induced at the same time as luciferase, providing strong evidence for a functional implication of aldehyde dehydrogenase in the bioluminescent system of B. harveyi.