Initial clinical experience of surface guided stereotactic radiation therapy with open-face mask immobilization for improving setup accuracy: a retrospective study.

Initial clinical experience of surface guided stereotactic radiation therapy with open-face mask immobilization for improving setup accuracy: a retrospective study.
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DOI:
10.1186/s13014-022-02077-4
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发表时间:
2022-06-04
期刊:
影响因子:
3.6
通讯作者:
Yue, Haizhen
Yue, Haizhen
中科院分区:
医学2区
文献类型:
--
作者:
Zhou, Shun;Li, Junyu;Zhu, Xianggao;Du, Yi;Yu, Songmao;Wang, Meijiao;Yao, Kaining;Wu, Hao;Yue, Haizhen

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提出一种带开放面罩固定的特定表面引导立体定向放射治疗(SRT)治疗程序,并评估提高摆位准确性的初步临床经验。回顾性分析48例SRT患者的治疗资料。对于每例患者,使用双壳开放式面罩实现头部固定。前壳保持开放,以暴露前额、鼻子、眼睛和颧骨。暴露的面部区域被用作AlignRT(VisionRT Inc,UK)进行表面跟踪的感兴趣区域。后壳提供了一个坚固和个性化的头枕。使用从计划CT图像上描绘的皮肤轮廓获得的参考表面,通过6DoF实时增量(RTD)引导患者初始设置。初始设置的终点在平移RTD中为1 mm,在旋转RTD中为1 °。进行CBCT引导以导出初始摆位误差,并在治疗输送前应用治疗床移位进行摆位校正。分析CBCT治疗床移位、AlignRT RTD值、复位率和设置时间。VRT、LNG、LAT、YAW、PITCH和ROLL中CBCT治疗床位移的绝对值中位数(最大值)分别为0.4(1.3)mm、0.1(2.5)mm、0.2(1.6)mm、0.1(1.2)度、0.2(1.4)度和0.1(1.3)度。治疗床移位和AlignRT RTD值显示出高度一致性,但VRT和PITCH(p值< 0.01)除外,其差异小至可忽略不计。我们没有发现任何患者重新定位是由于超出公差的设置错误,即,3 mm和2度。表面引导摆位时间范围为52 ~ 174 s,平均和中位时间分别为97.72 s和94 s。所提出的具有开放式面罩固定的表面引导SRT程序是在同一过程中提高患者舒适度和定位精度的一个进步。最大限度地减少了初始摆位误差和复位率,并具有合理的效率,可用于常规临床实践。
To propose a specific surface guided stereotactic radiotherapy (SRT) treatment procedure with open-face mask immobilization and evaluate the initial clinical experience in improving setup accuracy. The treatment records of 48 SRT patients with head lesions were retrospectively analyzed. For each patient, head immobilization was achieved with a double-shell open-face mask. The anterior shell was left open to expose the forehead, nose, eyes and cheekbones. The exposed facial area was used as region-of-interest for surface tracking by AlignRT (VisionRT Inc, UK). The posterior shell provided a sturdy and personalized headrest. Patient initial setup was guided by 6DoF real-time deltas (RTD) using the reference surface obtained from the skin contour delineated on the planning CT images. The endpoint of initial setup was 1 mm in translational RTD and 1 degree in rotational RTD. CBCT guidance was performed to derive the initial setup errors, and couch shifts for setup correction were applied prior to treatment delivery. CBCT couch shifts, AlignRT RTD values, repositioning rate and setup time were analyzed. The absolute values of median (maximal) CBCT couch shifts were 0.4 (1.3) mm in VRT, 0.1 (2.5) mm in LNG, 0.2 (1.6) mm in LAT, 0.1(1.2) degree in YAW, 0.2 (1.4) degree in PITCH and 0.1(1.3) degree in ROLL. The couch shifts and AlignRT RTD values exhibited highly agreement except in VRT and PITCH (p value < 0.01), of which the differences were as small as negligible. We did not find any case of patient repositioning that was due to out-of-tolerance setup errors, i.e., 3 mm and 2 degree. The surface guided setup time ranged from 52 to 174 s, and the mean and median time was 97.72 s and 94 s respectively. The proposed surface guided SRT procedure with open-face mask immobilization is a step forward in improving patient comfort and positioning accuracy in the same process. Minimized initial setup errors and repositioning rate had been achieved with reasonably efficiency for routine clinical practice.
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发表时间: 2018-01
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