Comparison of a basic and an advanced pharmacotherapy-related clinical decision support system in a hospital care setting in the Netherlands
Comparison of a basic and an advanced pharmacotherapy-related clinical decision support system in a hospital care setting in the Netherlands
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DOI：
10.1136/amiajnl-2011-000360
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发表时间：
2012-01-01
影响因子：
6.4
通讯作者：
De Smet, Peter A. G. M.
中科院分区：
文献类型：
--
作者：
Eppenga, Willemijn L.;Derijks, Hieronymus J.;De Smet, Peter A. G. M.
目的比较基本的和先进的临床决策支持系统（CDSS）中药物警报的临床相关性。设计A prospective observational study.Materials and Methods我们收集了4023药物订单在医院独立评估两个药物治疗相关的决策支持系统。只有更先进的系统在其算法中考虑了患者特征和实验室测试结果。两名药剂师评估了产生的药物警报的临床相关性。如果药剂师将采取措施（例如，联系医生或护士），则认为警报相关。主要分析涉及两个系统中临床相关药物警报的阳性预测值（PPV）。结果高级系统的PPV显着更高（5.8% vs 17.0%; p
Objective To compare the clinical relevance of medication alerts in a basic and in an advanced clinical decision support system (CDSS).Design A prospective observational study.Materials and methods We collected 4023 medication orders in a hospital for independent evaluation in two pharmacotherapy-related decision support systems. Only the more advanced system considered patient characteristics and laboratory test results in its algorithms. Two pharmacists assessed the clinical relevance of the medication alerts produced. The alert was considered relevant if the pharmacist would undertake action (eg, contact the physician or the nurse). The primary analysis concerned the positive predictive value (PPV) for clinically relevant medication alerts in both systems.Results The PPV was significantly higher in the advanced system (5.8% vs 17.0%; p