Potential radiotherapy improvements with respiratory gating
Potential radiotherapy improvements with respiratory gating
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DOI：
10.1007/bf03178368
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发表时间：
2002-03-01
影响因子：
--
通讯作者：
Mohan, R.
中科院分区：
文献类型：
--
作者：
Keall, P. J.;Kini, V. R.;Mohan, R.
门控是一种相对较新且潜在有用的治疗补充，适用于受分次内运动影响的区域的外束放射治疗。通过正弦运动球体的 CT 成像研究了门控对治疗边缘、图像伪影以及体积和位置精度的影响。球体的运动模拟目标运动。在动态移动球体的 CT 成像过程中，门控将静态体积再现到 1% 以内，而在不使用门控的情况下观察到超过 20% 的误差。使用边缘的理论分析，单独的门控或与电子射野成像设备组合可以使 CTV 到 PTV 边缘减少 2-11 毫米，因此需要照射的健康组织较少。门控可以减少治疗余量、提高图像质量以及提高大体肿瘤体积的位置和体积精度。
Gating is a relatively new and potentially useful therapeutic addition to external beam radiotherapy applied to regions affected by intra-fraction motion. The impact was of gating on treatment margins, image artifacts, and volume and positional accuracy was investigated by CT imaging of sinusoidally moving spheres. The motion of the spheres simulates target motion. During the CT imaging of dynamically moving spheres, gating reproduced the static volume to within 1%, whereas errors of over 20% were observed where gating was not used. Using a theoretical analysis of margins, gating alone or in combination with an electronic portal imaging device may allow a 2-11 mm reduction in the CTV to PTV margin, and thus less healthy tissue need be irradiated. Gating may allow a reduction of treatment margins, an improvement in image quality, and an improvement in positional and volumetric accuracy of the gross tumor volume.