Studies of metabolic turnover with tritium as a tracer. V. The predominantly non-dynamic state of body constituents in the rat.
Studies of metabolic turnover with tritium as a tracer. V. The predominantly non-dynamic state of body constituents in the rat.
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以氚为示踪剂进行代谢周转的研究。
DOI：
10.1016/s0021-9258(18)55655-6
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发表时间：
1956
期刊：
影响因子：
--
通讯作者：
R. Thompson
中科院分区：
文献类型：
--
作者：
J. Ballou;R. Thompson
成年小鼠在饲料中接受生理盐水中的氧化氚。氚的滞留量后来在身体水和干燥的身体中进行了估计。水体的生物半衰期约为1.1天。给药的氚“结合”到组织中的百分比是0-5%到1.0%。结合氚保留曲线显示两个主要的指数分量，表明半衰期约为9天和90天。它们分别代表了相对动态和相对稳定的身体成分。它们潜在的氚结合能力是相当大的。-D.邓肯。
Adult mice on stock diet received tritium oxide in physiological saline intraperitoneally. Reten tion of tritium was later estimated in body water and in the dry carcase. The biological half-life of body water was about 1.1 day. The percentage of administered tritium " bound " into tissue com pounds was0-5to 1.0. The curve of bound tritium retentions showed 2 major exponential components indicating half-lives of about9and90days. It is suggested that these represent relatively dynamic and relatively stable body constituents, respec tively. Their potential tritium-binding capacities are of comparable magnitude.-D. Duncan.