The UCSC Genome Browser Database: update 2006.

The UCSC Genome Browser Database: update 2006.
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DOI:
10.1093/nar/gkj144
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发表时间:
2006-01-01
影响因子:
14.9
通讯作者:
Kent WJ
Kent WJ
中科院分区:
生物学2区
文献类型:
--
作者:
Hinrichs AS;Karolchik D;Baertsch R;Barber GP;Bejerano G;Clawson H;Diekhans M;Furey TS;Harte RA;Hsu F;Hillman-Jackson J;Kuhn RM;Pedersen JS;Pohl A;Raney BJ;Rosenbloom KR;Siepel A;Smith KE;Sugnet CW;Sultan-Qurraie A;Thomas DJ;Trumbower H;Weber RJ;Weirauch M;Zweig AS;Haussler D;Kent WJ

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加州大学圣克鲁斯分校基因组浏览器数据库(GBD)包含大约12种脊椎动物和几种主要模式生物的基因组序列和注释数据。基因组注释通常包括组装数据、序列组成、基因和基因预测、mRNA和表达序列标记证据、比较基因组学、调控、表达和变异数据。数据库经过优化,支持与web工具的快速交互性能,这些工具为挖掘数据提供了强大的可视化和查询功能。基因组浏览器显示各种各样的注释在所有规模从单核苷酸水平到一个完整的染色体。Table Browser提供对数据库表和序列数据的直接访问,支持对全基因组数据集的复杂查询。蛋白质组浏览器图形显示蛋白质属性。基因分类器允许过滤和比较基因的几个指标,包括表达数据和几个基因特性。BLAT和In Silico PCR在几秒钟内搜索整个基因组的序列。这些工具是高度集成的,并提供许多到其他数据库和网站的超链接。GBD、浏览工具、可下载的数据文件以及文档和其他信息的链接可在以下网址找到。
The University of California Santa Cruz Genome Browser Database (GBD) contains sequence and annotation data for the genomes of about a dozen vertebrate species and several major model organisms. Genome annotations typically include assembly data, sequence composition, genes and gene predictions, mRNA and expressed sequence tag evidence, comparative genomics, regulation, expression and variation data. The database is optimized to support fast interactive performance with web tools that provide powerful visualization and querying capabilities for mining the data. The Genome Browser displays a wide variety of annotations at all scales from single nucleotide level up to a full chromosome. The Table Browser provides direct access to the database tables and sequence data, enabling complex queries on genome-wide datasets. The Proteome Browser graphically displays protein properties. The Gene Sorter allows filtering and comparison of genes by several metrics including expression data and several gene properties. BLAT and In Silico PCR search for sequences in entire genomes in seconds. These tools are highly integrated and provide many hyperlinks to other databases and websites. The GBD, browsing tools, downloadable data files and links to documentation and other information can be found at .