Response properties of dorsolateral pontine units during smooth pursuit in the rhesus macaque.
Response properties of dorsolateral pontine units during smooth pursuit in the rhesus macaque.
复制标题
恒河猴平稳追击过程中背外侧脑桥单位的响应特性。
DOI：
10.1152/jn.1988.60.2.664
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发表时间：
1988
影响因子：
2.5
通讯作者：
Wallman,J
中科院分区：
文献类型：
--
作者：
Mustari,MJ;Fuchs,AF;Wallman,J
1.桥脑背外侧核(DLPN)的解剖联系与顺畅追踪眼球运动的产生有关。它接受来自被认为参与视觉运动处理(中颞叶皮质)或运动执行(顶叶后皮质)的皮质结构的输入，并投射到参与平稳追踪的小脑小叶。为了确定DLPN在平滑追踪中的作用，我们研究了五只猴子的191个DLPN神经元的放电模式，这些神经元被训练成使一个点在有图案的背景或黑暗中移动时进行平滑追踪眼球运动。2.可区分出四种单位类型。视觉单位(15%)响应大的纹理图案的移动而放电，通常是以方向选择性的方式，但不是在黑暗中平稳地追逐一个点的过程中。31%的眼动神经元在黑暗中进行正弦平稳追踪时放电率最高，在眼位或眼速峰值时放电率最高，但在背景运动或其他视觉刺激时无反应。当目标短暂熄灭(消失)时，这些单位继续放电，猴子在黑暗中继续平稳地眼球运动。我们的大多数(54%)DLPN单位在猴子注视的同时，在黑暗和背景运动中顺利追逐时放电。在顺利追击过程中清空目标显示，这些单位分为两个截然不同的类别。视觉追逐单元在空白处停止放电，表明它们只有视觉敏感度。在空白期间，追踪和视觉单位继续放电，表明它们具有综合的动眼神经和视觉敏感度。3.在平稳追击中，95%的单位是方向选择性的。这些单元具有较宽的定向调谐曲线，半高宽度从65度到180度不等。虽然垂直和近垂直方向占主导地位，但仍可观察到许多DLPN单位的优先方向。4.对大视野背景运动作出反应的单位大多具有方向选择性。在大场背景的正弦运动中，其中一半的放电也与刺激速度有关，而另一半则不是。
1. The anatomical connections of the dorsolateral pontine nucleus (DLPN) implicate it in the production of smooth-pursuit eye movements. It receives inputs from cortical structures believed to be involved in visual motion processing (middle temporal cortex) or motion execution (posterior parietal cortex) and projects to the flocculus of the cerebellum, which is involved in smooth pursuit. To determine the role of the DLPN in smooth pursuit, we have studied the discharge patterns of 191 DLPN neurons in five monkeys trained to make smooth-pursuit eye movements of a spot moving either across a patterned background or in darkness. 2. Four unit types could be distinguished. Visual units (15%) discharged in response to movement of a large textured pattern, often in a direction-selective fashion but not during smooth pursuit of a spot in the dark. Eye movement neurons (31%) discharged during sinusoidal smooth pursuit in the dark with peak discharge rate either at peak eye position or peak eye velocity, but they showed no response during background movement or during other visual stimulation. These units continued to discharge when the target was extinguished (blanked) briefly, and the monkey continued to make smooth eye movements in the dark. The majority (54%) of our DLPN units discharged during both smooth pursuit in the dark and background movement while the monkey fixated. Blanking the target during smooth pursuit revealed that these units fell into two distinct classes. Visual pursuit units ceased discharging during a blank, suggesting that they had only a visual sensitivity. Pursuit and visual units continued to discharge during the blank, indicating that they had a combined oculomotor and visual sensitivity. 3. Ninety-five percent of the units that discharged during smooth pursuit were direction selective. These units had rather broad directional tuning curves with widths at half height ranging from 65 to 180 degrees. Many preferred directions for DLPN units were observed, although the vertical and near-vertical directions predominated. 4. Most units that responded to large-field background movement were direction selective. During sinusoidal movement of a large-field background, half of them also discharged in relation to stimulus velocity, whereas others did not.
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影响因子：
2.5
作者：
HARTING, JK
通讯作者：
HARTING, JK
影响因子：
2.5
作者：
HASHIKAWA, T
通讯作者：
HASHIKAWA, T
灵长类絮状在前庭眼反射快速行为改变中的作用。
影响因子：
2.5
作者：
S. Lisberger;A. Fuchs
通讯作者：
A. Fuchs
视动眼球震颤的方向不对称：发育变化以及与辅助视神经系统和前庭系统的关系
影响因子：
2.9
作者：
Josh Wallman 'and;Jose Velez
通讯作者：
Jose Velez
DOI：
10.1111/j.1749-6632.1981.tb30892.x
发表时间：
1981-01-01
影响因子：
5.2
作者：
NODA, H
通讯作者：
NODA, H