Releasing the Kraken.

Releasing the Kraken.
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DOI:
10.3389/fbinf.2021.808003
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发表时间:
2021
期刊:
FRONTIERS IN BIOINFORMATICS
影响因子:
--
通讯作者:
Wood, Derrick E
Wood, Derrick E
中科院分区:
其他
文献类型:
--
作者:
Salzberg, Steven L;Wood, Derrick E

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十年前,微生物基因组数量的急剧增加导致了一个转折点,当时在综合数据库中找到短而精确的匹配的方法变得与旧的,较慢的方法一样准确。新的想法导致了一种比以前快数百倍的方法。如今,精确的k-mer匹配是许多微生物组分析工具的核心标准技术。
Ten years ago, the dramatic rise in the number of microbial genomes led to an inflection point, when the approach of finding short, exact matches in a comprehensive database became just as accurate as older, slower approaches. The new idea led to a method that was hundreds of times times faster than those that came before. Today, exact k-mer matching is a standard technique at the heart of many microbiome analysis tools.