Electronic Interactions between π-Stacked DNA Base Pairs and Diphenylacetylene-4,4‘-dicarboxamide in Hairpin DNA
Electronic Interactions between π-Stacked DNA Base Pairs and Diphenylacetylene-4,4‘-dicarboxamide in Hairpin DNA
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发夹 DNA 中 π 堆叠 DNA 碱基对与二苯乙炔-4,4-二甲酰胺之间的电子相互作用
DOI：
10.1021/ja9924997
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发表时间：
1999
影响因子：
15
通讯作者：
M. Wasielewski
中科院分区：
文献类型：
--
作者：
F. Lewis;Xiaoyang Liu;Scott E. Miller;M. Wasielewski
B 型 DNA 的 {pi} 堆叠碱基对为电子转移的研究提供了独特的介质。最近对 DNA 中光诱导电子转移动力学的研究采用了与相邻碱基对 {pi} 堆叠的探针发色团。该方法是使用有机发色团作为发夹形成双（寡核苷酸）缀合物中的连接体。光谱研究、分子建模和晶体学支持有机发色团与相邻碱基对大致共面的发夹结构。
The {pi}-stacked base pairs of B-form DNA provide a unique medium for the investigation of electron transfer. Most recent investigations of the dynamics of photoinduced electron transfer in DNA have employed probe chromophores that are {pi}-stacked with an adjacent base pair. The approach has been to use organic chromophores as linkers in hairpin-forming bis(oligo-nucleotide) conjugates. A hairpin structure in which the organic chromophore is approximately coplanar with the adjacent base pair is supported by spectroscopic studies, molecular modeling, and crystallography.