Effect of randoms on signal-to-noise ratio in TOF PET
Effect of randoms on signal-to-noise ratio in TOF PET
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DOI：
10.1109/tns.2006.875066
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发表时间：
2006-06-01
影响因子：
1.8
通讯作者：
Conti, Maurizio
中科院分区：
文献类型：
--
作者：
Conti, Maurizio
飞行时间 (TOF) 正电子发射断层扫描 (PET) 具有提高信噪比 (SNR) 的潜力。在文献中，这种改进被估计为与 D/Delta x 的平方根成正比，其中 D 是要成像的物体的径向尺寸，Delta x 是与扫描仪的时间分辨率相关的空间不确定性。该估计不包括随机因素的影响。在本文中，我们讨论了随机重合在 TOF PET 中的作用；特别是，由于 TOF PET 的随机减少，信噪比得到了改善。我们介绍并讨论了这种改进的简单模型，修改了 SNR 增益的传统估计，并将其与具有 TOF 功能的西门子 Hi-Rez PET 扫描仪的实验数据进行了比较。
Time-of-flight (TOF) positron emission tomography (PET) has the potential to improve signal-to-noise ratio (SNR). In the literature, this improvement has been estimated as proportional to the square root of D/Delta x, where D is the radial dimension of the object to be imaged, and Delta x is the spatial uncertainty associated with the time resolution of the scanner. This estimate does not include the effect of the randoms. In this paper we discuss the role of random coincidence in TOF PET; in particular, the improvement in SNR due to random reduction in TOF PET. We introduce and discuss a simple model for this improvement, modify the traditional estimate for SNR gain, and compare it to experimental data from a Siemens Hi-Rez PET scanner with TOF capability.