Landscape of TB Infection and Prevention among People Living with HIV.
Landscape of TB Infection and Prevention among People Living with HIV.
复制标题
DOI:
10.3390/pathogens11121552
复制
发表时间:
2022-12-16
期刊:
影响因子:
--
通讯作者:
Kay A
中科院分区:
文献类型:
--
作者:
Vasiliu A;Abelman R;Kherabi Y;Iswari Saktiawati AM;Kay A
Tuberculosis (TB) is one of the leading causes of mortality in people living with HIV (PLHIV) and contributes to up to a third of deaths in this population. The World Health Organization guidelines aim to target early detection and treatment of TB among PLHIV, particularly in high-prevalence and low-resource settings. Prevention plays a key role in the fight against TB among PLHIV. This review explores TB screening tools available for PLHIV, including symptom-based screening, chest radiography, tuberculin skin tests, interferon gamma release assays, and serum biomarkers. We then review TB Preventive Treatment (TPT), shown to reduce the progression to active TB and mortality among PLHIV, and available TPT regimens. Last, we highlight policy-practice gaps and barriers to implementation as well as ongoing research needs to lower the burden of TB and HIV coinfection through preventive activities, innovative diagnostic tests, and cost-effectiveness studies.
登录
查看更多内容
影响因子:
11.8
作者:
Elzi, Luigia;Schlegel, Matthias;Furrer, Hansjakob
通讯作者:
Furrer, Hansjakob
影响因子:
158.5
作者:
Danel, Christine;Moh, Raoul;Anglaret, Xavier
通讯作者:
Anglaret, Xavier
影响因子:
34.3
作者:
Badje, Anani;Moh, Raoul;Anglaret, Xavier
通讯作者:
Anglaret, Xavier
影响因子:
15.8
作者:
Getahun H;Kittikraisak W;Heilig CM;Corbett EL;Ayles H;Cain KP;Grant AD;Churchyard GJ;Kimerling M;Shah S;Lawn SD;Wood R;Maartens G;Granich R;Date AA;Varma JK
通讯作者:
Varma JK
DOI:
10.5588/ijtld.16.0624
发表时间:
2017-02-01
影响因子:
4
作者:
Chiang, S. S.;Roche, S.;Lecca, L.
通讯作者:
Lecca, L.