Prevalence of and Risk Factors for Hepatitis B Viremia After Spontaneous Hepatitis B Surface Antigen Seroclearance in Hepatitis B Carriers

Prevalence of and Risk Factors for Hepatitis B Viremia After Spontaneous Hepatitis B Surface Antigen Seroclearance in Hepatitis B Carriers
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DOI:
10.1093/cid/cir755
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发表时间:
2012-01-01
影响因子:
11.8
通讯作者:
Liaw, Yun-Fan
Liaw, Yun-Fan
中科院分区:
医学1区
文献类型:
--
作者:
Chu, Chia-Ming;Liaw, Yun-Fan

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在 118 名既往乙型肝炎表面抗原 (HBsAg) 携带者中,低水平乙型肝炎 (HBV) 病毒血症在 HBsAg 血清清除后持续 10 年以上,持续时间为 15%-20%。抗 HBsAg 血清转换的患者(69 人中的 6 人 [8.7%])中 HBV 病毒血症的频率显着低于无血清转换的患者(49 人中的 15 人 [30.6%])。
In 118 previous hepatitis B surface antigen ( HBsAg) carriers, low-level hepatitis B (HBV) viremia persisted at a rate of 15%-20% for >10 years after HBsAg seroclearance. The frequency of HBV viremia was significantly (P = .002) lower in patients with anti-HBsAg seroconversion (6 of 69 [8.7%]) than in those without seroconversion (15 of 49 [30.6%]).