Re-evaluation of lecithins (E 322) as a food additive
Re-evaluation of lecithins (E 322) as a food additive
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DOI：
10.2903/j.efsa.2017.4742
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发表时间：
2017-04-01
期刊：
影响因子：
3.3
通讯作者：
Dusemund, Birgit
中科院分区：
文献类型：
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作者：
Mortensen, Alicja;Aguilar, Fernando;Dusemund, Birgit
本意见涉及卵磷脂（e322）作为食品添加剂使用时的重新评价。卵磷脂（E 322）是欧盟根据食品添加剂法规（EC） No 1333/2008附件II和附件III批准的食品添加剂，并于1973年由JECFA和1982年由SCF进行了评估。在卵磷脂中，磷脂酰胆碱在机体所有细胞中通过胞苷-5-二磷酸-胆碱途径水解成胆碱。根据欧盟委员会法规（EU） No 257/ 2010重新评估的某些食品添加剂风险评估的概念框架，小组得出结论认为，没有必要为卵磷脂（E 322）设定数值ADI，并且在对卵磷脂（E 322）作为食品添加剂的报告使用进行精细化暴露评估时，1岁以上的一般人群不存在安全问题。小组进一步得出结论，从卵磷脂（E 322）中提取的胆碱作为食品添加剂，在工业报告的使用和使用水平下，不存在安全问题。对于婴儿（从12周龄到11个月），专家小组的结论是，在精细化暴露评估中，对报告的卵磷脂（E 322）作为食品添加剂的使用，以及卵磷脂（E 322）作为食品添加剂的使用和工业报告的使用水平，没有安全问题。对于食用用于特殊医疗目的的食品的婴幼儿，评估小组得出结论认为，对所报告的卵磷脂（E 322）作为食品添加剂的使用和卵磷脂的这些使用（E 322）所产生的胆碱暴露进行的精细化接触评估不存在安全问题。(C) 2017年欧洲食品安全局。
The present opinion deals with the re-evaluation of lecithins (E 322) when used as a food additive. Lecithins (E 322) is an authorised food additive in the EU according to Annex II and Annex III to Regulation (EC) No 1333/2008 on food additives, and have been previously evaluated by JECFA in 1973 and by the SCF in 1982. Among lecithins, phosphatidylcholine is hydrolysed in choline in the cytidine-5-diphosphate-choline pathway in all cells of the body. Following the conceptual framework for the risk assessment of certain food additives re-evaluated under Commission Regulation (EU) No 257/ 2010, the Panel concluded that there was no need for a numerical ADI for lecithins (E 322) and that there was no safety concern for the general population from more than 1 year of age at the refined exposure assessment for the reported uses of lecithins (E 322) as a food additive. The Panel further concluded that there is no safety concern for the exposure to the choline from lecithins (E 322) as a food additive at use and use levels reported by industry. For infants (from 12 weeks up to 11 months of age), the Panel concluded that there was no safety concern at the refined exposure assessment for the reported uses of lecithins (E 322) as a food additive and for the choline from lecithins (E 322) as a food additive at use and use levels reported by industry. For infants and young children consuming foods for special medical purposes, the Panel concluded that there was no safety concern with respect to the refined exposure assessment for the reported uses of lecithins (E 322) as a food additive and for exposure to choline resulting from these uses of lecithins (E 322). (C) 2017 European Food Safety Authority.