Application of low copy number STR typing to the identification of aged, degraded skeletal remains
Application of low copy number STR typing to the identification of aged, degraded skeletal remains
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DOI：
10.1111/j.1556-4029.2007.00561.x
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发表时间：
2007-11-01
影响因子：
1.6
通讯作者：
Parsons, Thomas J.
中科院分区：
文献类型：
--
作者：
Irwin, Jodi A.;Leney, Mark D.;Parsons, Thomas J.
在降解骨骼遗骸方法的开发验证过程中，低拷贝数 (LCN) STR 分型已成功应用于四个有趣的病例。每个案例都解决了具体问题，STR 数据的获取主要作为任何特定情况下的额外确认或调查信息，而不一定提供确定身份的明确证据。这些案件涉及第一次世界大战、第二次世界大战和越南战争中失踪的美国军人。这些案件的多样性，从所涉及的问题、遗骸的年龄以及可供比较的参考材料的类型来看，证明了 LCN STR 分型在鉴定失踪人员退化骨骼遗骸方面的广泛用途。
Low copy number (LCN) STR typing was successfully applied to four interesting cases during developmental validation of the approach for degraded skeletal remains. Specific questions were addressed in each case, with the acquisition of STR data largely serving as additional confirmatory or investigatory information in any specific situation, and not necessarily providing the definitive evidence to establish identity. The cases involve missing U. S. service members from World War I, World War II, and the Vietnam War. The variety of these cases, in terms of the questions addressed, the age of the remains, and the type of reference material available for comparison, demonstrates the broad utility of LCN STR typing in the identification of degraded skeletal remains from missing persons.