Expeditious synthesis of porphyrin-cobaltacarborane conjugates
Expeditious synthesis of porphyrin-cobaltacarborane conjugates
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DOI：
10.1039/b415649h
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发表时间：
2005-01-01
影响因子：
4.9
通讯作者：
Vicente, MGH
中科院分区：
文献类型：
--
作者：
Hao, E;Vicente, MGH
通过亲核开环反应2，高收率制备了两个卟啉-钴碳硼烷偶联物5和6。这些新型富硼荧光化合物在肿瘤硼中子俘获治疗中作为硼递送剂具有潜在的应用前景。
Two porphyrin - cobaltacarborane conjugates 5 and 6 were prepared in high yields via a nucleophilic ring-opening reaction of 2. These novel boron-rich and fluorescent compounds have potential application as boron delivery agents for the boron neutron capture therapy of tumors.