Purpose in life is associated with mortality among community-dwelling older persons.
Purpose in life is associated with mortality among community-dwelling older persons.
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DOI：
10.1097/psy.0b013e3181a5a7c0
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发表时间：
2009-06
影响因子：
3.3
通讯作者：
Bennett DA
中科院分区：
文献类型：
--
作者：
Boyle PA;Barnes LL;Buchman AS;Bennett DA
评估生活目标作为健康结果的重要决定因素与社区居住老年人死亡率之间的关系。我们使用了来自两项纵向队列研究（拉什记忆和老龄化项目和少数民族老龄化研究）的1238名无痴呆症老年人的数据，对生活目的进行了基线评估，并进行了长达5年的随访，以检验以下假设：生活目的更大与社区居住老年人死亡风险降低相关。基线时生活目标测量的平均值±标准差评分为3.7 ± 0.5（范围= 2 - 5），评分越高表明生活目标越大。在5年随访期间（平均= 2.7年），1238人中有151人（12.2%）死亡。在调整了年龄、性别、教育和种族的比例风险模型中，更高水平的生活目标与死亡风险的大幅降低相关（风险比= 0.60，95%置信区间= 0.42，0.87）。因此，在生活目标测量中得分高的人（得分= 4.2，第90百分位数）的危险率约为得分低的人（得分= 3.1，第10百分位数）的危险率的57%。生活目标与死亡率的关联在男性和女性之间，白人和黑人之间没有差异。此外，在添加了几个潜在混杂因素（包括抑郁症状、残疾、神经质、慢性疾病数量和收入）后，这一发现仍然存在。在社区居住的老年人中，更大的生活目标与降低全因死亡风险有关。
To assess the association between purpose in life as an important determinant of health outcomes and mortality in community-dwelling elderly persons. We used data from 1238 older persons without dementia from two longitudinal cohort studies (Rush Memory and Aging Project and Minority Aging Research Study) with baseline evaluations of purpose in life and up to 5 years of follow-up to test the hypothesis that greater purpose in life is associated with a reduced risk of mortality among community-dwelling older persons. The mean ± standard deviation score on the purpose in life measure at baseline was 3.7 ± 0.5 (range = 2−5), with higher scores indicating greater purpose in life. During the 5-year follow-up (mean = 2.7 years), 151 of 1238 persons (12.2%) died. In a proportional hazards model adjusted for age, sex, education, and race, a higher level of purpose in life was associated with a substantially reduced risk of mortality (hazard ratio = 0.60, 95% Confidence Interval = 0.42, 0.87). Thus, the hazard rate for a person with a high score on the purpose in life measure (score = 4.2, 90th percentile) was about 57% of the hazard rate of a person with a low score (score = 3.1, 10th percentile). The association of purpose in life with mortality did not differ among men and women or Whites and Blacks. Further, the finding persisted after the addition of terms for several potential confounders, including depressive symptoms, disability, neuroticism, the number of chronic medical conditions, and income. Greater purpose in life is associated with a reduced risk of all-cause mortality among community-dwelling older persons.