The Epidemiology of Dengue in the Americas Over the Last Three Decades: A Worrisome Reality
The Epidemiology of Dengue in the Americas Over the Last Three Decades: A Worrisome Reality
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DOI：
10.4269/ajtmh.2010.09-0346
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发表时间：
2010-01-01
影响因子：
3.3
通讯作者：
Guzman, Maria G.
中科院分区：
文献类型：
--
作者：
Luis San Martin, Jose;Brathwaite, Olivia;Guzman, Maria G.
我们报告了1980年至2007年美洲地区登革热病的流行模式。报告给泛美卫生组织的登革热病例分析了三个时期：1980-1989（80年代），1990-1999（90年代）和2000-2007（2000-7）。年龄分布数据来自巴西、委内瑞拉、洪都拉斯和墨西哥。随着时间的推移，病例增加：1，033，417（80年代）至2，725，405（90年代）至4，759，007（2000-7）。据报告，20世纪80年代，西裔加勒比地区的浓度最高（39.1%），90年代（55%）和2000- 2007年（62.9%）转移到南锥体。从1980年到1987年，报告了242例死亡，而2000年至2007年期间为1,391例。最常分离的血清型为DENV-1和DENV-2（90年代）以及DENV-2和DENV-3（2000-7年）。发病率最高的是青少年和年轻人;在委内瑞拉，登革出血热的发病率最高的是婴儿。近几十年来，美洲的登革热发病率/死亡率不断上升。
We have reported the epidemic patterns of dengue disease in the Region of the Americas from 1980 through 2007. Dengue cases reported to the Pan American Health Organization were analyzed from three periods: 1980-1989 (80s), 1990-1999 (90s), and 2000-2007 (2000-7). Age distribution data were examined from Brazil, Venezuela, Honduras, and Mexico. Cases increased over time: 1,033,417 (80s) to 2,725,405 (90s) to 4,759,007 (2000-7). The highest concentrations were reported in the Hispanic Caribbean (39.1%) in the 80s shifting to the Southern Cone in the 90s (55%) and 2000-7 (62.9%). From 1980 through 1987, 242 deaths were reported compared with 1,391 during 2000-7. The most frequently isolated serotypes were DENV-1 and DENV-2 (90s) and DENV-2 and DENV-3 (2000-7). The highest incidence was observed among adolescents and young adults; dengue hemorrhagic fever incidence was highest among infants in Venezuela. Increasing dengue morbidity/mortality was observed in the Americas in recent decades.