Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes
Oxidative cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with toluenes, ethers, aliphatic alcohols or simple alkanes
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DOI：
10.1039/d0qo00535e
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发表时间：
2020-07
影响因子：
5.4
通讯作者：
Wen-Jin Xia;Yangchun Xin;Zhiwei Zhao;Xin Chen;Xiang-xiang Wang;Yi Li;Guanlin Wang;Ya-Min Li
中科院分区：
文献类型：
--
作者：
Wen-Jin Xia;Yangchun Xin;Zhiwei Zhao;Xin Chen;Xiang-xiang Wang;Yi Li;Guanlin Wang;Ya-Min Li
描述了2-氰基-3-芳基苯胺衍生丙烯酰胺与碳氢化合物的氧化自由基级联环化反应。该反应的底物范围很广，甲苯、醚、脂肪醇和简单烷烃都可以作为偶联剂，从而得到烷基取代吡啶[4,3,2-gh]菲菲啶。
An oxidative radical cascade cyclization of 2-cyano-3-arylaniline derived acrylamides with hydrocarbons is described. The present reaction exhibits a wide substrate scope, and toluenes, ethers, aliphatic alcohols and simple alkanes can be employed as coupling partners, providing access to alkyl substituted pyrido[4,3,2-gh]phenanthridines.