Impaired Cerebral Autoregulation Using Near-Infrared Spectroscopy and Its Relation to Clinical Outcomes in Premature Infants
Impaired Cerebral Autoregulation Using Near-Infrared Spectroscopy and Its Relation to Clinical Outcomes in Premature Infants
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DOI：
10.1007/978-1-4419-7756-4_31
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发表时间：
2011-01-01
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影响因子：
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通讯作者：
Van Huffel, Sabine
中科院分区：
文献类型：
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作者：
Caicedo, Alexander;De Smet, Dominique;Van Huffel, Sabine
为了检测新生儿脑自动调节功能受损，使用相关、相干和部分相干方法研究了平均动脉血压（MABP）和脑血流（CBF）变化之间的一致性。通过使用记录时间的临界百分比（CPRT）来评估是否存在受损的自动调节。CBF的变化通过测量脑血管内氧合（HbD）、局部脑氧饱和度（rSO（2））和脑组织氧合（TOI）的变化来反映，如通过近红外光谱（NIRS）（INVOS4100和NIRO300）测量的。研究早产儿自身调节功能受损与远期临床结局的关系。
The concordance between the change in the Mean Arterial Blood Pressure (MABP) and the Cerebral Blood Flow (CBF) is studied using the Correlation, Coherence and Partial Coherence methods in order to detect Impaired Cerebral Autoregulation in Neonates. The presence of impaired autoregulation is assessed by the use of the Critical Percentage of Recording Time (CPRT). The changes in CBF are reflected by the measurement of changes in cerebral intravascular oxygenation (HbD), regional cerebral oxygen saturation (rSO(2)), and cerebral tissue oxygenation (TOI), as measured by Near-Infrared Spectroscopy (NIRS) (INVOS4100 and NIRO300). The relation between impaired autoregulation and long term clinical outcomes in premature infants is studied.