The Hutchinson Smoking Prevention Project trial: design and baseline characteristics.
The Hutchinson Smoking Prevention Project trial: design and baseline characteristics.
复制标题
哈钦森预防吸烟项目试验：设计和基线特征。
DOI：
10.1006/pmed.2000.0664
复制
发表时间：
2000
影响因子：
5.1
通讯作者：
Kealey,KA
中科院分区：
文献类型：
--
作者：
Mann,SL;PetersonJr,AV;Marek,PM;Kealey,KA
IntroductionThis paper describes the experimental design and baseline characteristics of the哈钦森吸烟预防项目（HSPP），一项为期15年的试验，以确定在多大程度上以3-12年级为基础的学校烟草使用预防干预可以阻止整个高中和高中以后的烟草使用。纳入学区的全部三年级学生，整个原始队列的长期随访，以及解释学区内终点的组随机化和组内相关性的样本大小和评估方法。以理论为基础的干预是教师为主导的，包括3-10年级的课程单元，教师培训，9-12年级的烟草使用戒烟材料，和高中工作人员newslets.ResultsBaseline数据收集在试验队列的8388名儿童和他们的父母和40个合作学区和社区。实验conditions.ConclusionsThe HSPP试验的实验设计之间的基线变量的分布的比较显示出良好的平衡将提供一个严格的测试的干预。实验和对照条件之间基线变量的平衡将有助于保证定于2000年发表的试验干预效果结果将是公正的。
IntroductionThis paper describes the experimental design and baseline characteristics of the Hutchinson Smoking Prevention Project (HSPP), a 15-year trial to determine to what extent a grade 3–12 school-based tobacco use prevention intervention can deter tobacco use throughout and beyond high school.DesignTrial design features include use of the school district as the unit of randomization, inclusion of the school district's entire enrollment of 3rd graders, long-term follow-up of the entire original cohort, and sample size and evaluation methods that account for the group-randomization and intraclass correlation of endpoints within school districts. The theory-based intervention is teacher-led and includes grade 3–10 curriculum units, teacher training, grade 9–12 tobacco use cessation materials, and high school staff newsletters.ResultsBaseline data were collected on the trial cohort of 8388 children and their parents and on the 40 collaborating school districts and communities. A comparison of the distribution of baseline variables between experimental conditions shows good balance.ConclusionsThe HSPP trial's experimental design will provide a rigorous test of the intervention. The balance in baseline variables between the experimental and control conditions will help provide assurance that the trial's intervention effectiveness results, scheduled for publication in 2000, will be unbiased.