Silver-containing dressings and the need for evidence
Silver-containing dressings and the need for evidence
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DOI：
10.1097/00000446-200612000-00025
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发表时间：
2006-12-01
影响因子：
2.7
通讯作者：
Hermans, Michel H.
中科院分区：
文献类型：
--
作者：
Hermans, Michel H.
伤口护理领域已经被“活性”敷料淹没，这些敷料将生物活性物质递送到伤口部位，并且已经对那些含有银的敷料给予了很多关注。银是一种广谱试剂：它对大量革兰氏阳性和革兰氏阴性微生物、许多需氧菌和厌氧菌以及几种耐药性菌株具有杀菌作用。目前有超过10种含纯银的敷料可供使用;所有敷料均声称通过银的抗菌活性促进伤口愈合。但是关于银抗菌功效的研究结果往往是不确定的或相互矛盾的。因此，临床医生如何决定哪种敷料最适合每位患者？提出了文献综述的评分系统。
The field of wound care has been inundated with "active" dressings-those that deliver biologically active substances to the wound site-and much attention has been given to those containing silver. Silver is a broad-spectrum agent: it is bactericidal to a large number of Gram-positive and Gram-negative microorganisms, many aerobes and anaerobes, and several antibiotic-resistant strains. More than 10 dressings containing pure silver are currently available; all claim to enhance wound healing through the antimicrobial activity of silver. But research findings on silver's antimicrobial efficacy are often inconclusive or contradictory. How, therefore, can clinicians decide which dressing is most appropriate for each patient? A grading system for reviewing the literature is presented.