BASE-LINE VISUAL-FIELD PROFILE OF OPTIC NEURITIS - THE EXPERIENCE OF THE OPTIC NEURITIS TREATMENT TRIAL
BASE-LINE VISUAL-FIELD PROFILE OF OPTIC NEURITIS - THE EXPERIENCE OF THE OPTIC NEURITIS TREATMENT TRIAL
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DOI：
10.1001/archopht.1993.01090020085029
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发表时间：
1993-02-01
影响因子：
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通讯作者：
BECK, RW
中科院分区：
文献类型：
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作者：
KELTNER, JL;JOHNSON, CA;BECK, RW
本研究的目的是确定448例急性视神经炎患者的基线视野特征，这些患者参加了视神经炎治疗试验。对患眼和对侧眼视野缺损的严重程度和类型进行分类。患眼弥漫性视野缺损占48.2%，中央或盲中心暗点占8.3%，垂直或其他神经纤维束型缺损占20.1%，其他各种缺损占23.4%。448例患者中有308例（68.8%）在基线时对侧眼存在视野受累。2.9%的患者存在视交叉或视交叉后视野缺损的证据。由于视神经炎急性发作时可出现各种各样的视野缺损，因此视野缺损的模式在区分视神经炎与缺血性视神经病变和其他视神经疾病方面的效用有限。对侧眼无症状的视野缺损很常见。
The purpose of the present study was to determine the baseline visual field characteristics in 448 patients with acute optic neuritis who were entered into the Optic Neuritis Treatment Trial. The severity and pattern of visual field loss in both the affected and fellow eyes were classified. For affected eyes, diffuse visual field loss was present in 48.2% of eyes, central or centrocecal scotoma was present in 8.3% of eyes, altitudinal or other nerve-fiber bundle-type defects were present in 20.1% of eyes, and a variety of other defects were present in 23.4% of eyes. Visual field involvement was present in the fellow eye at baseline in 308 (68.8%) of the 448 patients. Evidence of a chiasmal or retrochiasmal visual field defect was present in 2.9% of the patients. Since a wide variety of visual field defects can occur with an acute attack of optic neuritis, the pattern of visual field loss is of limited utility in distinguishing optic neuritis from ischemic optic neuropathy and other optic nerve disorders. Asymptomatic visual field defects in the fellow eye are common.