Factors Influencing IACUC Decision Making: Who Leads the Discussions?
Factors Influencing IACUC Decision Making: Who Leads the Discussions?
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DOI：
10.1177/1556264617717827
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发表时间：
2017-10-01
影响因子：
1.3
通讯作者：
Maranda, Louise
中科院分区：
文献类型：
--
作者：
Silverman, Jerald;Lidz, Charles W.;Maranda, Louise
关于在研究中适当使用动物的决定主要由机构动物护理和使用委员会（IACUC）做出。一些评论家声称，科学家对IACUC的决定施加了过度的影响。我们研究了来自10个IACUC的87个方案审查，以评估是否有任何一组参与者似乎主导了方案讨论。会议的录音经过编码，以记录讨论的主题。我们发现，动物研究科学家的主题提及总数最多，而社区成员的最少。按人均计算，主席和主治兽医提到的最多。科学家们提出了数量最多的协议，随后的讨论往往包含与发言中提到的相同的主题。科学家提交的大量方案及其在方案讨论期间提出的评论总数表明，科学家可能会显著影响IACUC的决策。
Decisions about the appropriate use of animals in research are largely made by Institutional Animal Care and Use Committees (IACUCs). Several commentators claim that scientists exert excessive influence on IACUC decisions. We studied 87 protocol reviews from 10 IACUCs to assess whether any group of participants appeared to dominate the protocol discussions. Audio recordings of the meetings were coded to capture the topics of the discussions. We found that animal research scientists made the largest total number of topic mentions while community members made the fewest. On a per person basis, chairpersons and attending veterinarians made the most mentions. Scientists presented the largest number of protocols, and the subsequent discussions tended to contain the same topics mentioned in the presentations. The large number of protocols presented by scientists and their total number of comments made during protocol discussions suggest that scientists may significantly influence IACUC decision making.