Resting blood flow in hypocontractile myocardium: resolving the controversy.
Resting blood flow in hypocontractile myocardium: resolving the controversy.
复制标题
低收缩心肌的静息血流量：解决争议。
DOI：
10.1161/circulationaha.105.583344
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发表时间：
2005
期刊：
影响因子：
37.8
通讯作者：
Klocke,FrancisJ
中科院分区：
文献类型：
--
作者：
Klocke,FrancisJ
冠状动脉疾病患者的存活非缺血心肌在静息条件下是否会出现血流量减少的问题已经争论了三十年。一些早期测量报告静息左心室流量减少，这似乎很难归因于疤痕组织与正常灌注的心肌的混合。 1, 2 其他人未能显示表面上正常的个体和冠心病患者之间的差异。 3, 4 2019 世纪 70 年代末观察到的静息 201Tl 扫描中的短暂缺陷支持了存活的非缺血心肌相对灌注不足的概念。它们“通常与严重的冠状动脉疾病有关，但左心室壁运动正常或仅轻度异常”5，并且在旁路移植手术后通常不那么明显。 6
The question of whether reductions in blood flow occur under resting conditions in viable nonischemic myocardium in patients with coronary artery disease has been debated for 3 decades. Some early measurements reported reductions in resting left ventricular flow that seemed difficult to attribute to admixture of scar tissue with normally perfused myocardium. 1, 2 Others failed to show differences between apparently normal individuals and coronary patients. 3, 4 Transient defects in resting 201Tl scans observed in the late 1970s supported the concept of relative hypoperfusion of viable nonischemic myocardium. They were “usually associated with severe coronary artery disease but normal or only mildly abnormal left ventricular wall motion” 5 and often were less pronounced after bypass graft surgery. 6