The changing face of acoustic neuroma management in the USA: Analysis of the 1998 and 2008 patient surveys from the acoustic neuroma association
The changing face of acoustic neuroma management in the USA: Analysis of the 1998 and 2008 patient surveys from the acoustic neuroma association
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DOI：
10.3109/02688697.2013.815323
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发表时间：
2014-01-01
影响因子：
1.1
通讯作者：
Agazzi, Siviero
中科院分区：
文献类型：
--
作者：
Patel, Jaymin;Vasan, Rohit;Agazzi, Siviero
Objective.最近对国家癌症中心登记处监测流行病学和最终结果（SEER）数据库的回顾显示，在美国，25%的听神经瘤（AN）通过观察进行管理。有几篇文章质疑这些生长缓慢的肿瘤的积极治疗。人们担心SEER数据库中的数据可能偏向于治疗，因为选择观察的患者不太可能在癌症中心就诊。为了尝试和调整这种潜在的偏见，我们决定在美国使用听神经瘤协会（ANA）进行的患者调查来调查AN的管理趋势。研究设计.数据库审查。方法.对1998年和2008年ANA患者调查的数据进行分析，以检测肿瘤大小和治疗方式之间的趋势。管理趋势，包括观察，显微手术切除和放射治疗的基础上，肿瘤大小的标准进行了检查。结果在本研究期间，诊断时肿瘤大小显著减小（1966-1998：23.8%）。
Objective. A recent review of the national cancer center registry Surveillance Epidemiology and End Results (SEER) database revealed that in the United States, 25% of Acoustic Neuromas (AN) are managed with observation. Several articles have questioned the aggressive treatment of these slow growing tumors. Concern has been raised that data from the SEER database might be biased towards treatment as patients who chose observation are less likely to be seen at a cancer center. To try and adjust for this potential bias, we decided to investigate management trends of AN in the United States using patient surveys conducted by the Acoustic Neuroma Association (ANA). Study design. Database review. Methods. Data from the 1998 and 2008 ANA patient's surveys were analyzed to detect trends between tumor size and treatment modality. Management trends including observation, microsurgical resection and radiation were examined as well based on tumor size criteria. Results. During this study period, tumor size at diagnosis decreased significantly (1966-1998: 23.8%