Active efflux of antimicrobial agents in wild-type strains of enterococci
Active efflux of antimicrobial agents in wild-type strains of enterococci
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DOI：
10.1128/aac.41.4.869
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发表时间：
1997-04-01
影响因子：
4.9
通讯作者：
Nikaido, H
中科院分区：
文献类型：
--
作者：
Lynch, C;Courvalin, P;Nikaido, H
肠球菌对许多抗菌药物具有内在耐药性。我们研究了能量依赖性流出的放射性标记的药物从四个参考菌株的粪肠球菌和屎肠球菌菌株，发现大多数菌株泵出诺氟沙星和氯霉素。仅在某些菌株中检测到四环素外排。
Enterococci are intrinsically resistant to numerous antimicrobial agents. We examined the energy-dependent efflux of radiolabeled drugs from four reference strains of Enterococcus faecalis and a strain of Enterococcus faecium and found that most strains pumped out norfloxacin and chloramphenicol. Efflux of tetracycline was detected only in certain strains.