Vibrational monitor of early demineralization in tooth enamel after in vitro exposure to phosphoridic liquid
Vibrational monitor of early demineralization in tooth enamel after in vitro exposure to phosphoridic liquid
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DOI：
10.1016/j.saa.2016.08.036
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发表时间：
2017-02-15
影响因子：
4.4
通讯作者：
Kanamura, Narisato
中科院分区：
文献类型：
--
作者：
Pezzotti, Giuseppe;Adachi, Tetsuya;Kanamura, Narisato
应用拉曼光谱法对离体健康人牙齿的脱矿程度进行了定量评价。基于之前对拉曼选择规则的评估（由取向分布函数（ODF）统计算法授权）和新提出的对羟磷灰石六边形结构的选定振动模式的声子态密度（PDOS）的分析，对体外暴露于高酸性饮料（即，CocaCola（TM）Classic，pH = 2.5）。拉曼方法被证明是非常敏感的，并且光谱特征可能与釉质表面结构的非化学计量的增加直接相关，因为脱矿过程的非常早期阶段（即，当对于其它常规分析技术还不可见时）。所提出的拉曼光谱算法可能具有一定的通用性龋齿风险评估，允许在牙科中迅速的非接触式诊断实践。(C)2016爱思唯尔B.V.保留所有权利。
The Raman spectroscopic method has been applied to quantitatively assess the in vitro degree of demineralization in healthy human teeth. Based on previous evaluations of Raman selection rules (empowered by an orientation distribution function (ODF) statistical algorithm) and on a newly proposed analysis of phonon density of states (PDOS) for selected vibrational modes of the hexagonal structure of hydroxyapatite, a molecular-scale evaluation of the demineralization process upon in vitro exposure to a highly acidic beverage (i.e., CocaCola (TM) Classic, pH = 2.5) could be obtained. The Raman method proved quite sensitive and spectroscopic features could be directly related to an increase in off-stoichiometry of the enamel surface structure since the very early stage of the demineralization process (i.e., when yet invisible to other conventional analytical techniques). The proposed Raman spectroscopic algorithm might possess some generality for caries risk assessment, allowing a prompt non -contact diagnostic practice in dentistry. (C) 2016 Elsevier B.V. All rights reserved.