Synthesis of 2-hydroxymalonic acid derivatives via tandem oxidation and rearrangement by photo organic catalysis
Synthesis of 2-hydroxymalonic acid derivatives via tandem oxidation and rearrangement by photo organic catalysis
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DOI：
10.1039/c6ra07084a
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发表时间：
2016-04
期刊：
影响因子：
3.9
通讯作者：
Akifumi Okada;Y. Nagasawa;Tomoaki Yamaguchi;E. Yamaguchi;N. Tada;T. Miura;A. Itoh
中科院分区：
文献类型：
--
作者：
Akifumi Okada;Y. Nagasawa;Tomoaki Yamaguchi;E. Yamaguchi;N. Tada;T. Miura;A. Itoh
本文报道了一种温和的方法，用催化量的亚甲基蓝和可见光照射，使β-氧代酯直接转化为相应的2-羟基丙二酸酯，丙醇二酸酯。此外，β-氧代酰胺也被转化为相应的2-羟基丙二酸酯酰胺。
This report describes a mild method for the direct transformation of β-oxoesters to the corresponding 2-hydroxymalonic esters, tartronic esters, using singlet oxygen produced by a catalytic amount of methylene blue and visible light irradiation using fluorescent lamps. In addition, β-oxoamides were also converted to the corresponding 2-hydroxymalonic ester amides.