MICE REARED WITH RATS ELIMINATION OF ODORS VISION AND AUDITION AS SIGNIFICANT STIMULUS SOURCES
MICE REARED WITH RATS ELIMINATION OF ODORS VISION AND AUDITION AS SIGNIFICANT STIMULUS SOURCES
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DOI：
10.1002/dev.420020107
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发表时间：
1969-01-01
影响因子：
2.2
通讯作者：
ROSENBERG K M
中科院分区：
文献类型：
--
作者：
DENENBERG V H;PASCHKE R;ROSENBERG K M
先前的研究发现，由哺乳期大鼠母亲饲养和哺乳的小鼠，或在非哺乳期成年雌性大鼠存在的情况下饲养的小鼠，对新刺激的肾上腺皮质反应明显小于对照小鼠。本文的目的是确定这种现象是否可以介导的刺激，不需要成年大鼠和年轻的小鼠之间的身体接触。实验小鼠出生并饲养在一个笼子里，通过双层网壁将它们与成年非哺乳期雌性大鼠分开。因此，他们可以看到，听到，闻到老鼠，但没有身体接触是可能的。对照小鼠在成年非泌乳雌性小鼠存在的情况下以类似方式饲养。在断奶时，两组对新刺激的皮质酮反应几乎相同。这些数据支持这样的假设，即小鼠和大鼠之间的直接身体接触是引起小鼠生理和行为变化所必需的。
Prior research has found that mice reared and nursed by a lactating rat mother, or reared in the presence of a nonlactating adult female rat, give a significantly smaller adrenocortical response to a novel stimulus than do control mice. The purpose of this paper was to determine whether this phenomenon could be mediated through stimuli that do not require physical contact between the adult rat and the young mouse. Experimental mice were born and reared in a cage that separated them from an adult nonlactating female rat by means of a double mesh wall. Thus, they could see, hear, and smell the rat, but no physical contact was possible. Control mice were reared similarly in the presence of an adult nonlactating female mouse. At the time of weaning the corticosterone response of both groups to a novel stimulus was virtually identical. The data support the hypothesis that direct physical contact between the mouse and rat is necessary to cause physiological and behavioral changes in the mouse.