Incidence rates of arterial and venous thrombosis after diagnosis of systemic lupus erythematosus

Incidence rates of arterial and venous thrombosis after diagnosis of systemic lupus erythematosus
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DOI:
10.1002/art.21314
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发表时间:
2005-08-15
期刊:
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子:
--
通讯作者:
Fortin, PR
Fortin, PR
中科院分区:
其他
文献类型:
--
作者:
Sarabi, ZS;Chang, E;Fortin, PR

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据报道,7.2-12%的系统性红斑狼疮(SLE)患者发生血栓形成(1-3)。在一项为期10年的SLE患者前瞻性队列研究中,最常见的死亡原因是活动性SLE(26.5%)、血栓形成(26.5%)和感染(25%),血栓形成在第二个5年随访期占主导地位(4)。SLE诊断后血栓形成的发生率尚不清楚。我们报告了SLE患者初始队列中动脉和静脉血栓形成的年发病率。
Thrombosis has been reported in 7.2–12% of persons with systemic lupus erythematosus (SLE)(1–3). In a 10-year prospective cohort study of patients with SLE, the most frequent causes of death were active SLE (26.5%), thrombosis (26.5%), and infection (25%), with thrombosis dominating the second 5-year period of followup (4). The incidence rates of thrombosis after a diagnosis of SLE remain unknown. We report the yearly incidence of arterial and venous thrombosis in an inception cohort of patients with SLE.