[A case of repeated bilateral pneumothorax associated with upper lobe predominant fibrosis in an aluminum processing worker].
[A case of repeated bilateral pneumothorax associated with upper lobe predominant fibrosis in an aluminum processing worker].
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铝加工工人反复双侧气胸伴上叶纤维化1例[J].
DOI：
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
M. Fujimura
中科院分区：
文献类型：
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作者：
Kanako Inuzuka;M. Yasui;Y. Waseda;Hazuki Takato;Yukari Ichikawa;M. Fujimura
患者男，39岁，在铝加工行业工作18年，2007年3月2日因右胸痛来我院就诊。发现右侧气胸复发，他住院治疗。由于气胸经保守治疗后并未改善，因此成功进行了电视辅助胸腔镜活检和右上叶切除术。肺实质塌陷，肺纤维化，淋巴细胞聚集在滤泡中。根据元素分析结果，我们诊断为铝肺。认为下叶过度扩张伴上叶纤维化是由铝沉积引起的。我们判断他的病情严重，我们开始用25 mg/天的泼尼松龙（PSL）和120 mg/天的环孢素（CyA）治疗。在撰写本文时，他是一名门诊患者，正在接受5 mg/天PSL和160 mg/天CyA方案的监测，未发生任何肺纤维化进展或气胸复发。
A 39-year-old man, who had been working in an aluminum processing industry for 18 years, visited our hospital for right chest pain on March 2, 2007. A relapse of right pneumothorax was found, and he was hospitalized. As the pneumothorax did not improve with conservative treatment, video-assisted thoracoscopic biopsy and suturing of the right upper lobe were successfully performed. The pulmonary parenchyma had collapsed, there was pulmonary fibrosis, and lymphocytes had gathered in follicules. Based on elemental analysis results, we diagnosed aluminum lung. It was thought that overexpansion of the lower lobe with the predominant upper lobe fibrosis was caused by the aluminum deposition. We judged his condition to be serious and we started treatment with 25 mg/day prednisolone (PSL), and 120 mg/day cyclosporine (CyA). At the time of writing, he is an outpatient, and is being monitored on a regimen of 5 mg/day PSL and 160 mg/day CyA without any progression of pulmonary fibrosis or relapse of pneumothorax.