Dynamic pulmonary perfusion and flow quantification with MR imaging, 3.0T vs. 1.5T: Initial results
Dynamic pulmonary perfusion and flow quantification with MR imaging, 3.0T vs. 1.5T: Initial results
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DOI：
10.1002/jmri.20645
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发表时间：
2006-08-01
影响因子：
4.4
通讯作者：
Finn, J. Paul
中科院分区：
文献类型：
--
作者：
Nael, Kambiz;Michaely, Henrik J.;Finn, J. Paul
目的：前瞻性评价3.0 T与1.5 T下肺时间分辨MR血管造影（MRA）和肺动脉（PA）血流定量的技术可行性和相对性能。材料和方法：肺循环的时间分辨对比增强（CE）MRA，在1.5和3.0特斯拉下对14名连续的成年健康志愿者进行主PA（MPA）的血流定量，序列参数几乎相同。图像质量，信噪比（SNR），肺灌注，流量和速度的定量指标进行了评价和比较，在两个磁场strengths.Results：时间分辨肺MRA，灌注和流量定量成功地进行了两个磁场。两种磁场下的肺灌注和血流指数结果相当，无统计学显著差异。3.0 T时血管结构的SNR值高于1.5 T（P = 0.001）。在3.0 T时，实质增强的SNR值和清晰度评分显著较低（分别为P = 0.008和0.001）。结论：在3.0 T时进行时间分辨肺MRA、灌注和血流定量是可行的，结果与1.5 T相当。在3.0 T下较低的实质增强被认为反映了在较高磁场下增加的磁化率效应。需要进一步的工作，以充分利用肺灌注成像在3.0 T的潜力，并解决目前的局限性。
Purpose: To prospectively evaluate the technical feasibility and relative performance of pulmonary time-resolved MR angiography (MRA) and pulmonary artery (PA) flow quantification at 3.0 T vs. 1.5 T.Materials and Methods: Time-resolved contrast-enhanced (CE) MRA of the pulmonary circulation, and flow quantification of the main PA (MPA) were performed in 14 consecutive adult healthy volunteers at both 1.5 and 3.0 Tesla with nearly identical sequence parameters. Image quality, signal-to-noise ratio (SNR), and quantitative indices of pulmonary perfusion, flow, and velocity were evaluated and compared at both field strengths.Results: Time-resolved pulmonary MRA, perfusion, and flow quantification were successfully performed at both magnetic fields. The results of pulmonary perfusion and flow indices were comparable at both magnetic fields, with no statistically significant difference. The SNR values for vascular structures were higher at 3.0 T vs. 1.5 T (P = 0.001). The SNR values and the definition scores for parenchymal enhancement were significantly lower (P = 0.008 and 0.001, respectively) at 3.0 T.Conclusion: Time-resolved pulmonary MRA, perfusion, and flow quantification at 3.0 T was feasible, with comparable results to 1.5 T. The lower parenchymal enhancement at 3.0 T is believed to reflect increased susceptibility effects at higher magnetic fields. Further work is needed to fully exploit the potential of pulmonary perfusion imaging at 3.0 T and to address the current limitations.