VEIN INVASION IN RENAL-CELL CARCINOMA - IMPACT ON METASTATIC BEHAVIOR AND SURVIVAL
VEIN INVASION IN RENAL-CELL CARCINOMA - IMPACT ON METASTATIC BEHAVIOR AND SURVIVAL
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DOI：
10.1016/s0022-5347(01)66749-1
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发表时间：
1995-11-01
影响因子：
6.6
通讯作者：
ROOS, G
中科院分区：
文献类型：
--
作者：
LJUNGBERG, B;STENLING, R;ROOS, G
目的：肾细胞癌的血栓延伸至静脉是公认的。我们研究了单独的静脉侵犯对生存没有不利影响的假设，但在其他肿瘤中是一个高度负面的因素。材料与方法：对连续200例患者的肾静脉、腔静脉侵犯情况进行评价，并与临床病程进行比较。结果：腔静脉侵犯26例，肾静脉侵犯47例。静脉侵犯患者的生存期明显较短，但没有基于受累程度的生存期差异。结论：我们的研究表明，静脉侵犯本身似乎是肾细胞癌的一个重要预后因素。
Purpose: The development of a thrombus extending into the veins is well recognized in renal cell carcinoma. We investigated the hypothesis that vein invasion alone has no adverse impact on survival but is a highly negative factor in other tumors.Materials and Methods: In 200 consecutive patients invasion of the renal vein and vena cava was evaluated and compared with the clinical course.Results: A total of 26 patients had vena caval and 47 had renal vein invasion. Patients with venous invasion had a significantly shorter survival but no survival difference was demonstrated based on the level of involvement.Conclusions: Our study indicates that vein invasion itself seems to be an important prognostic factor in renal cell carcinoma.