Clostridium perfringens enterotoxin damages the human intestine in vitro

Clostridium perfringens enterotoxin damages the human intestine in vitro
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DOI:
10.1128/iai.73.12.8407-8410.2005
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发表时间:
2005-12-01
影响因子:
3.1
通讯作者:
Ibarra, C
Ibarra, C
中科院分区:
医学2区
文献类型:
--
作者:
Miyakawa, MEF;Creydt, VP;Ibarra, C

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在体外,产气荚膜梭菌肠毒素(CPE)与人回肠上皮结合,诱导形态损伤,同时降低短路电流、经上皮阻力和净吸水率。CPE在体外也能与人结肠结合,但只引起轻微的形态和转运变化,这在统计学上并不显著。
In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport changes that are not statistically significant.