Branched-Chain Amino Acid Supplementation Before Squat Exercise and Delayed-Onset Muscle Soreness
Branched-Chain Amino Acid Supplementation Before Squat Exercise and Delayed-Onset Muscle Soreness
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DOI：
10.1123/ijsnem.20.3.236
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发表时间：
2010-06-01
影响因子：
2.5
通讯作者：
Mawatari, Kazunori
中科院分区：
文献类型：
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作者：
Shimomura, Yoshiharu;Inaguma, Asami;Mawatari, Kazunori
作者使用 12 名年轻、健康、未经训练的女性参与者研究了支链氨基酸 (BCAA) 补充剂对深蹲运动引起的迟发性肌肉酸痛 (DOMS) 的影响。该实验采用交叉双盲设计进行。运动当天早上，参与者在深蹲运动前摄入 100 毫克/公斤体重的 BCAA（异亮氨酸：亮氨酸：缬氨酸 = 1：2.3：1.2）或糊精，共 7 组，每组 20 次，组间间隔 3 分钟。在两项试验中，DOMS 在第 2 天和第 3 天均达到峰值，但 BCAA 试验中的酸痛程度明显低于安慰剂。运动后 2 天（第 3 天）测量最大自主等长收缩期间的腿部肌肉力量，补充 BCAA 抑制了安慰剂试验中观察到的肌肉力量下降（与对照条件下记录的值的 80% 相似）。安慰剂试验中运动后血浆 BCAA 浓度下降，而 BCAA 试验中运动后 2 小时血浆 BCAA 浓度显着升高。在安慰剂中，血清肌红蛋白浓度因锻炼而增加，但在 BCAA 试验中则没有。在两项试验中，作为中性粒细胞活化指标的血浆弹性蛋白酶浓度似乎在深蹲运动后有所增加，但弹性蛋白酶水平的变化仅在安慰剂试验中才显着。这些结果表明补充支链氨基酸可以抑制肌肉损伤。
The authors examined the effect of branched-chain amino acid (BCAA) supplementation on squat-exercise-induced delayed-onset muscle soreness (DOMS) using 12 young, healthy, untrained female participants. The experiment was conducted with a crossover double-blind design. In the morning on the exercise-session day, the participants ingested either BCAA (isoleucine:leucine:valine = 1:2.3:1.2) or dextrin at 100 mg/kg body weight before the squat exercise, which consisted of 7 sets of 20 squats/set with 3-min intervals between sets. DOMS showed a peak on Days 2 and 3 in both trials, but the level of soreness was significantly lower in the BCAA trial than in the placebo. Leg-muscle force during maximal voluntary isometric contractions was measured 2 d after exercise (Day 3), and the BCAA supplementation suppressed the muscle-force decrease (to similar to 80% of the value recorded under the control conditions) observed in the placebo trial. Plasma BCAA concentrations, which decreased after exercise in the placebo trial, were markedly elevated during the 2 hr postexercise in the BCAA trial. Serum myoglobin concentration was increased by exercise in the placebo but not in the BCAA trial. The concentration of plasma elastase as an index of neutrophil activation appeared to increase after the squat exercise in both trials, but the change in the elastase level was significant only in the placebo trial. These results suggest that muscle damage may be suppressed by BCAA supplementation.