Antimicrobial Resistance of Escherichia coli Urinary Isolates in the Veterans Affairs Health Care System
Antimicrobial Resistance of Escherichia coli Urinary Isolates in the Veterans Affairs Health Care System
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DOI：
10.1128/aac.02236-16
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发表时间：
2017-05-01
影响因子：
4.9
通讯作者：
LaPlante, Kerry L.
中科院分区：
文献类型：
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作者：
Morrill, Haley J.;Morton, Jacob B.;LaPlante, Kerry L.
我们回顾了来自127个住院和门诊设施的近300，000个临床大肠杆菌尿液分离株（2009年至2013年收集）的数据，以评估退伍军人事务部医疗保健系统患者使用临床和实验室标准研究所和疾病控制和预防中心国家医疗保健安全网络定义或指南的抗生素耐药性。对阿莫西林或氨苄西林/β-内酰胺酶抑制剂的耐药率约为40%，对氟喹诺酮类和甲氧苄啶-磺胺甲恶唑的耐药率接近30%。呋喃妥因、青霉素/β-内酰胺酶抑制剂和碳青霉烯类抗生素的耐药率仍低于10%。被认为是多重耐药的分离株的百分比各不相同（4%至37%），这取决于所使用的定义。
We reviewed data for almost 300,000 clinical Escherichia coli urinary isolates (collected in 2009 through 2013) from 127 inpatient and outpatient facilities, to assess antibiotic resistance among Veterans Affairs health care system patients using Clinical and Laboratory Standards Institute and Centers for Disease Control and Prevention National Healthcare Safety Network definitions or guidance. Rates of resistance to amoxicillin or ampicillin/beta-lactamase inhibitors were approximately 40% and rates of resistance to fluoroquinolones and trimethoprim-sulfamethoxazole approached 30%. Rates of resistance to nitrofurantoin, antipseudomonal penicillin/beta-lactamase inhibitors, and carbapenems remained less than 10%. The percentage of isolates that were considered multidrug resistant varied (4% to 37%), depending on the definitions used.