Head segmentation in vertebrates.
Head segmentation in vertebrates.
复制标题
脊椎动物的头部分割。
DOI：
10.1093/icb/icn036
复制
发表时间：
2008
影响因子：
2.6
通讯作者：
Schilling,Thomas
中科院分区：
文献类型：
--
作者：
Kuratani,Shigeru;Schilling,Thomas
脊椎动物头部分割的经典理论清楚地例证了20世纪以前比较胚胎学的理想主义本质。比较胚胎学的目的是识别所有脊椎动物共有的基本的初级结构，无论是作为原型还是祖先的发育模式。现代进化发育(EVO-DEVO)研究也是基于比较，因此有将复杂的胚胎解剖学简化为过于简单的模式的趋势。这里，在脊索动物中又一次寻找到了头部的基本节段性计划。我们召集了一次研讨会，在许多不同的进化和发展背景下，聚集了处理这个问题的主要研究人员。在这里，我们给出一个结果和领域的地位在这个现代的Evo-Devo的概述。我们强调头部分割问题尚未完全解决的事实，并讨论了寻找走出这一迷宫的线索的新方向。
Classic theories of vertebrate head segmentation clearly exemplify the idealistic nature of comparative embryology prior to the 20th century. Comparative embryology aimed at recognizing the basic, primary structure that is shared by all vertebrates, either as an archetype or an ancestral developmental pattern. Modern evolutionary developmental (Evo-Devo) studies are also based on comparison, and therefore have a tendency to reduce complex embryonic anatomy into overly simplified patterns. Here again, a basic segmental plan for the head has been sought among chordates. We convened a symposium that brought together leading researchers dealing with this problem, in a number of different evolutionary and developmental contexts. Here we give an overview of the outcome and the status of the field in this modern era of Evo-Devo. We emphasize the fact that the head segmentation problem is not fully resolved, and we discuss new directions in the search for hints for a way out of this maze.