In menstrual cycle stage a confounder in population-based psychiatric research?
In menstrual cycle stage a confounder in population-based psychiatric research?
复制标题
月经周期阶段是基于人群的精神病学研究中的混杂因素吗？
DOI：
10.1017/s003329179700514x
复制
发表时间：
1997
影响因子：
6.9
通讯作者：
Levav,I
中科院分区：
文献类型：
--
作者：
Schwartz,S;Lincoln,A;Levav,I
研究背景有人认为，月经周期中的控制点的失败可能导致在评估妇女精神症状时产生偏倚，因为与经前症状相关的状态影响可能导致症状报告的不可靠性以及症状评分的人为升高。我们研究这些假设，并在何种程度上，他们可以解释性别差异的症状量表得分的士气低落和enervation.MethodsThe数据是来自1949年和1958年之间出生在以色列的犹太人的流行病学研究。2265名男性和1769名女性（368月经前，458月经和943月经后）的症状量表评分进行了比较，关于可靠性，同质性和平均score.ResultsThere月经组之间没有差异，或男性和女性之间，在可靠性的α系数和变异系数测量他们的反应。女性组间平均症状量表评分无显著差异。每个女性组的平均量表得分显着高于平均scores for men.ConclusionsOur结果表明，月经周期阶段不影响报告的可靠性，反应的变异性或平均症状水平。然而，我们的结论可能不适用于药物作用的研究或经前烦躁的临床研究。
BackgroundIt has been suggested that a failure to control for point in the menstrual cycle can lead to biased results in assessing psychiatric symptoms among women since state affects associated with premenstrual symptoms may lead to unreliability of symptom reporting as well as an artificial elevation of symptom ratings. We examine these hypotheses and the extent to which they can account for gender differences in symptom scale scores of demoralization and enervation.MethodsThe data are derived from an epidemiological study of Jews born in Israel between 1949 and 1958. The symptom scale scores of 2265 men and 1769 women (368 premenstrual, 458 menstruation and 943 postmenstrual) were compared regarding reliability, homogeneity and mean score.ResultsThere were no differences among the menstrual groups, or between the men and women, in reliability of their responses as measured by the alpha coefficient and the coefficient of variation. There were no significant differences among the female groups on mean symptom scale score. The mean scale scores for each female group were significantly higher than the mean scores for men.ConclusionsOur results suggest that menstrual cycle stage does not influence the reliability of reporting, the variability of response or mean symptom levels. However, our conclusions may not apply to studies of drug effects or clinical studies of premenstrual dysphoria.