EFFECTS OF EMOTIONAL DISCRIMINATION TASKS ON CEREBRAL BLOOD-FLOW - REGIONAL ACTIVATION AND ITS RELATION TO PERFORMANCE
EFFECTS OF EMOTIONAL DISCRIMINATION TASKS ON CEREBRAL BLOOD-FLOW - REGIONAL ACTIVATION AND ITS RELATION TO PERFORMANCE
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DOI：
10.1006/brcg.1994.1036
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发表时间：
1994-07-01
影响因子：
2.5
通讯作者：
GUR, RE
中科院分区：
文献类型：
--
作者：
GUR, RC;SKOLNICK, BE;GUR, RE
面部辨别任务被用作生理神经成像过程中的激活探针（“神经行为探针”）。刺激物描绘了专业演员和女演员，构成了快乐和悲伤的情绪程度。皮质脑血流量（CBF）测定使用氙-133吸入法在休息基线，两个情绪（高兴从中性和悲伤从中性的面孔）和一个非情绪的歧视任务（年龄）。三项任务使CBF增加超过基线，右半球增加更大（任务x半球相互作用，p = .0001）。存在区域特异性效应（任务x区域x半球相互作用，p = 0.022）。相对于年龄歧视任务，这两个情绪歧视任务与更大的右顶叶激活。此外，相对于悲伤的辨别任务，快乐的辨别任务会诱发更大的左额叶激活。虽然整体幅度的CBF增加并没有表现出区域特定的相关性与性能，偏侧性确实表现出这种特异性。悲伤的歧视性能与更大的右顶叶激活，而快乐的歧视任务的性能与左额叶激活。年龄辨别能力与较高的激活右颞叶CBF相关。这些结果支持了右半球参与面部处理的假设，并进一步表明区域特定的半球参与快乐和悲伤的情绪歧视。这项研究强调了效用的性能指标，了解生理神经影像学研究中的激活效应的行为意义。(C)1994年出版社出版。
Facial discrimination tasks were applied as activation probes during physiologic neuroimaging (''neurobehavioral probes''). The stimuli pictured professional actors and actresses, posing degrees of happy and sad emotion. Cortical cerebral blood flow (CBF) was determined using the Xenon-133 inhalation method during resting baseline, two emotional (happy from neutral and sad from neutral faces) and one nonemotional discrimination task (age). The three tasks produced CBF increase over baseline, which was greater in the right hemisphere (Task x Hemisphere interaction, p = .0001). There were regionally specific effects (Task x Region x Hemisphere interaction, p = .022). Relative to the age discrimination task, both emotion discrimination tasks were associated with greater right parietal activation. In addition, the happy discrimination task induced greater left frontal activation relative to the sad discrimination task. While overall magnitude of CBF increase did not show regionally specific correlations with performance, laterality did show such specificity. Sad discrimination performance correlated with greater right parietal activation, while performance on the happy discrimination task correlated with left frontal activation. Age discrimination performance correlated with higher activated right temporal CBF. These results support the hypothesis of right hemispheric involvement in facial processing and further suggest regionally specific hemispheric participation in happy and sad emotional discrimination. The study underscores the utility of performance measures for understanding the behavioral significance of activation effects in physiologic neuroimaging studies. (C) 1994 Academic Press, Inc.