L-ASPARAGINASE-DEFICIENT MUTANTS OF YEAST
L-ASPARAGINASE-DEFICIENT MUTANTS OF YEAST
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DOI：
10.1126/science.167.3915.181
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发表时间：
1970-01-01
期刊：
影响因子：
56.9
通讯作者：
MORTIMER, RK
中科院分区：
文献类型：
--
作者：
JONES, GE;MORTIMER, RK
酵母L-天冬酰胺酶是一种多聚体酶，目前只发现了一个结构基因，已分离到14个L-天冬酰胺酶缺陷突变体，并在酿酒酵母遗传图谱上定位于同一位点。L-天冬酰胺酶基因（aspl）位于片段2上距离色氨酸合成基因（trp 4）约18厘摩的位置。
Yeast L-asparaginase is a multimeric enzyme for which only a single structural gene has been found. Fourteen mutants deficient in L-asparaginase have been isolated, and they have been located at one site on the genetic map of Saccharomyces cerevisiae. The L-asparaginase gene (aspl) is located about 18 centimorgans from a gene governing tryptophan synthesis (trp4) on fragment 2 of the map.