Genetics of Aux/IAA and ARF action in plant growth and development
Genetics of Aux/IAA and ARF action in plant growth and development
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DOI：
10.1023/a:1015255030047
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发表时间：
2002-06-01
影响因子：
5.1
通讯作者：
Reed, JW
中科院分区：
文献类型：
--
作者：
Liscum, E;Reed, JW
近年来，我们对生长素信号反应途径的理解取得了巨大进展。这些新知识大多来自对拟南芥突变体的研究。突变已被确定在各种各样的生长素反应组件，包括生长素转运蛋白，蛋白激酶和磷酸酶，泛素蛋白酶体途径的组成部分，和转录调节因子。本文综述了影响生长素调节的转录因子，特别是生长素/IAA和生长素反应因子（ARF）基因的突变。这些相关基因家族成员的突变体表现出的表型表明，在整个植物发育过程中（从胚胎发生到开花），既有独特的局部功能，也有重叠的冗余功能。在生化和生理水平上的Aux/IAA和ARF蛋白功能的特定突变的影响进行了讨论。我们还将讨论这些突变体所建议的生长素和光响应途径之间的相互作用的潜在机制。
Dramatic advances in our understanding of auxin signal-response pathways have been made in recent years. Much of this new knowledge has come through the study of mutants in Arabidopsis thaliana. Mutations have been identified in a wide variety of auxin-response components, including auxin transporters, protein kinases and phosphatases, components of a ubiquitin-proteosome pathway, and transcriptional regulators. This review focuses on mutations that affect auxin-modulated transcription factors, in particular those in the Aux/IAA and AUXIN RESPONSE FACTOR (ARF) genes. Mutants in members of these related gene families exhibit phenotypes that indicate both unique localized functions, as well as overlapping redundant functions, throughout plant development - from embryogenesis to flowering. Effects of specific mutations on Aux/IAA and ARF protein functions at the biochemical and physiological levels will be discussed. We will also discuss potential mechanisms for interactions between auxin and light response pathways that are suggested by these mutants.